Paranthaman Muralithararam

Certified Base SAS Programmer with over 7 years of experience in the Clinical Research Organization (CRO) sector, specializing in Statistical Programming and Clinical Data Management (CDM). Expertise includes interpreting study protocols, Statistical Analysis Plans (SAPs), and shells to produce CDISC-compliant datasets (SDTM, ADaM) and TLF reports focused on safety and efficacy. Proficient in developing and optimizing complex SAS programs and macros to standardize datasets according to study requirements, while collaborating effectively with cross-functional teams to manage project meetings and support resource planning. Demonstrated leadership as a Lead/Co-Lead programmer across multiple studies, with a proven ability to mentor and train associate programmers. Strong skills in Python, R, and SQL enhance analytical problem-solving capabilities.

ICON PLC, Chennai, India [12/2019 to 05/2021]:

• Recognized twice as “Star Performer” for outstanding contributions and performance excellence.
• Honored with the “ICON Inspire Award” for exceptional achievement and dedication.

• Collaborating Multiple Graphs” – Presented to the Global Biostatistics Department, Premier Research (2023-10).
• Customizing SAS Plots A Beginner’s Guide to DATTRMAP and SGANO” – Delivered presentation to the Global Biostatistics Department, Premier Research (2023-03).
• Application of AI/ML and NLP in Clinical Trials” – Presented at PHUSE-India Single-day event, Pfizer, Chennai (2022-12).

• Extensive experience in writing specification and programming across multiple SDTM domains.
• Trial Domains and Special Purpose Domains
• Interventions: EX, EC, CM, and PR.
• Events: AE, MH, DS, VE and DV.
• Findings: LB, QS, NV, FT, IE, MB, SC, DA, EG, VS, PC and PE.
• Developed EPOCH and VISIT macro as study specific.

• Extensive experience in programming and specification writing for safety and efficacy ADaM domains.
• ADSL, ADCM, ADAE, ADLB, ADVS, ADEFF, ADQS and ADMI.

• Tables: Developed Demographics, Disposition, Adverse Events, Concomitant Medications, Laboratory Summaries/Shift Tables, and Efficacy Tables utilizing advanced SAS procedures (PROC ANCOVA, PROC GLM, PROC RANK, PROC UNIVARIATE for residual analysis, PROC NPAR1WAY for Hodges–Lehmann Estimator, and PROC MIXED).
• Extensive experience in developing efficacy tables within Alzheimer’s and Neurology therapeutic areas.
• Listings: Development of medium-to-complex level listings
• Figures: Creation of spaghetti plots, survival plots, and compilation of study-specific figure reports.

• Neurology (Co-Lead Programmer) – Co-led all programming activities, including SDTM, ADaM, and TLF development, and managed eSUB package preparation and delivery.
• Psychiatry (Key Team Member) – Actively involved in all programming activities across SDTM, ADaM, and TLF outputs, contributing to high-quality eSUB submissions.
• Alzheimer’s Disease (Lead Programmer) – Directed all programming tasks for SDTM, ADaM, and TLF development; oversaw preparation and submission of eSUB packages.
• Oncology (Key Team Member) – Participated in all programming activities, providing expertise in updating and enhancing ADaM datasets and TLFs.
• Dermatology (Co-Lead Programmer) – Oversaw and contributed to all SDTM programming activities, supporting eSUB package submissions in compliance with regulatory standards.